Latest Immediate Publications in BJ Central

as at 9 September 2010

What are Biochemical Journal Immediate Publications and how should they be cited?

8 September 2010

Prevention of diabetic nephropathy in Ins2^+/-AkitaJ mice by the mitochondria-targeted therapy Mito Q.

Balu Chacko, Colin Reily, Anup Srivastava, Michelle S. Johnson, Elena Ulasova, Anupam Agarwal, Kurt Zinn, Michael P Murphy, Balaraman Kalyanaraman and Victor Darley-Usmar

7 September 2010

Akt inhibitors reduce glucose uptake independently of their effects on Akt

Shi-Xiong Tan, Yvonne Ng and David E. James

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

Sharon A Matthews, Maria N Navarro, Linda V Sinclair, Elizabeth A Emslie, Maria Carmen Feijoo-Carnero and Doreen Cantrell

MicroRNA-7 targets insulin-like growth factor 1 receptor (IGF1R) in tongue squamous cell carcinoma cells

Lu Jiang, Xiqiang Liu, Zujian Chen, Yi Jin, Caroline E Heidbreder, Antonia Kolokythas, Anxun Wang, Yang Dai and Xiaofeng Zhou

6 September 2010

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron

Darius J.R. Lane, Stephen R. Robinson, Hania Czerwinska, Glenda M. Bishop and Alfons Lawen

Interaction with receptor for activated C kinase 1 (RACK1) sensitises PDE4D5 towards hydrolysis of cyclic AMP and activation by protein kinase C

Rebecca J Bird, George S. Baillie and Stephen J Yarwood

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17 but is not a lipid raft-associated event

Catherine Anne Parr-Sturgess, David James Rushton and Edward Thomas Parkin

The Friedreich’s Ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

René Thierbach, Gunnar Drewes, Markus Fußer, Anja Voigt, Doreen Kuhlow, Urte Blume, Tim J Schulz, Carina Reiche, Hansruedi Glatt, Bernd Epe, Pablo Steinberg and Michael Ristow

Characterization of a novel peroxisome membrane protein essential for conversion of isopenicillin N to cephalosporin C

Ricardo V. Ullán, Fernando Teijeira, Susana M. Guerra, Inmaculada Vaca and Juan F. Martín

3 September 2010

Site-specific modification of calmodulin Ca²⁺ affinity tunes the skeletal muscle ryanodine receptor activation profile

Jie Jiang, Yubin Zhou, Jin Zou, Yanyi Chen, Priya Patel, Jenny J. Yang and Edward M Balog

Peptidoglycan derived from Staphylococcus epidermidis induces Connexin43 hemichannel activity with consequences on the innate immune response in endothelial cells

Jennifer Robertson, Sue Lang, Peter A Lambert and Patricia E Martin

Functional dissection of the N-terminal degron of human thymidylate synthase

Sandra P. Melo, Asami Yoshida and Franklin G. Berger

Functional domains of yeast hexokinase 2

Rafael Peláez, Pilar Herrero and Fernando Moreno

Regulation of the tumour suppressor Fbw7α by PKC dependent phosphorylation and cancer associated mutation

Joanne Durgan and Peter J Parker

2 September 2010

Chondroitin sulfate N-Acetylgalactosaminyltransferase-1 is required for normal cartilage development

Yumi Watanabe, Kosei Takeuchi, Susumu Higa Onaga, Michiko Sato, Mika Tsujita, Manabu Abe, Rie Natsume, Minqi Li, Tatsuya Furuichi, Mika Saeki, Tomomi Izumikawa, Ayumi Hasegawa, Minesuke Yokoyama, Shiro Ikegawa, Kenji Sakimura, Norio Amizuka, Hiroshi Kitagawa and Michihiro Igarashi

Similarities and differences in the structure and function of 4.1G and 4.1R¹³⁵, two protein 4.1 paralogs expressed in erythroid cells

Wataru Nunomura, Kengo Kinoshita, Marilyn Parra, Philippe Gascard, Xiuli An, Narla Mohandas and Yuichi Takakuwa

1 September 2010

Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferases 7 involved in the progeroid form of the Ehlers-Danlos syndrome

Sophie Rahuel-Clermont, Franck Daligault, Marie-Helene Piet, Sandrine Gulberti, Patrick Netter, Guy Branlant, Jacques Magdalou and Virginie Lattard

Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leukocytes through a common receptor

Valentina Arfilli, Domenica Carnicelli, Laura Rocchi, Francesca Ricci, Pasqualepaolo Pagliaro, Pier Luigi Tazzari and Maurizio Brigotti

Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification

Karin E. van Straaten, Hongyan Zheng, David R.J. Palmer and David A.R. Sanders

27 August 2010

The role of vicinal tyrosine residues in the function of Haemophilus influenzae ferric binding protein A

Husain K. Khambati, Trevor F. Moraes, Jagroop Singh, Stephen R Shouldice, Rong-hua Yu and Anthony B. Schryvers

Lysophosphatidylcholines activate G2A inducing GαI-1-/GαQ/11- Ca2+flux, Gβγ -Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs

Samina Y Khan, Nathan JD McLaughlin, Marguerite R Kelher, Phillip C Eckels, Fabia Gamboni-Robertson, Anirban Banerjee and Christopher C Silliman

26 August 2010

Antagonistic Roles of the ERK and p38 MAPK Signaling Pathways in Globin Expression, Heme Biosynthesis and Iron Uptake

Louay Mardini, Jadwiga Gasiorek, Anna Derjuga, Lucie Carrière, Matthias Schranzhofer, Barry H Paw, Prem Ponka and Volker Blank

Transcriptional Activation Requires Protection of the TATA-binding Protein Tbp1 by the Ubiquitin-specific Protease Ubp3

Boon Shang Chew, Wee Leng Siew, Benjamin Xiao and Norbert Lehming

Receptor guanylyl cyclase-G expressed in Grueneberg ganglion olfactory subsystem is activated by bicarbonate

Ying-Chi Chao, Chien-Ju Cheng, Hsiu-Ting Hsieh, Chih-Ching Lin, Chien-Chang Chen and Ruey-Bing Yang

Inhibition of the Mitochondrial Permeability Transition by Protein Kinase A in Rat Liver Mitochondria and Hepatocytes

Peter Pediaditakis, Jae-Sung Kim, Lihua He, Xun Zhang, Lee M Graves and John J. Lemasters

Subunit composition of an ECF-type biotin transporter analyzed in living bacteria

Friedrich Finkenwirth, Olivia Neubauer, Julia Gunzenhäuser, Janna Schoknecht, Silvia Scolari, Martin Stöckl, Thomas Korte, Andreas Herrmann and Thomas Eitinger

24 August 2010

Enhancement of latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution

Yumewo Suzuki, Kuniko Asada, Junichi Miyazaki, Takeo Tomita, Tomohisa Kuzuyama and Makoto Nishiyama

Lipin proteins form homo- and hetero-oligomers

Guang-Hui Liu, Jing Qu, Anne E Carmack, Hyun Bae Kim, Chang Chen, Hongmei Ren, Andrew J Morris, Brian N Finck and Thurl E Harris

The Chaperone Proteins HSP70, HSP40/DnaJ, and GRP78/BiP Suppress Misfolding and Formation of β-sheet-containing Aggregates by Human Amylin: a potential role for defective chaperone biology in type 2 diabetes

Vita Chien, Jacqueline F Aitken, Shaoping Zhang, Christina Buchanan, Anthony Hickey, Thomas Brittain, Garth JS Cooper and Kerry M Loomes

20 August 2010

RNA silencing of hydrogenase(-like) genes and investigation of their physiological roles in the green alga Chlamydomonas reinhardtii

James E Godman, Attila Molnár, David C Baulcombe and Janneke Balk

The HDHD1 gene, often deleted in X-linked ichthyosis, encodes a pseudouridine-5’-phosphatase

Alice Preumont, Rim Rzem, Didier Vertommen and Emile Van Schaftingen

Masking of the Fc region in human IgG4 by constrained X-ray scattering modelling: implications for antibody function and therapy

Yuki Abe, Jayesh Gor, Daniel G Bracewell, Stephen J Perkins and Paul A. Dalby

13 August 2010

Domain structure elucidation of human decorin glycosaminoglycans

Tatiana N Laremore, Mellisa Ly, Zhenqing Zhang, Kemal Solakyildirim, Scott A McCallum, Richard T Owens and Robert J Linhardt

12 August 2010

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate binding sites in a ganglioside dependent manner

Jasmin Strotmeier, Kwangkook Lee, Anne K. Völker, Stefan Mahrhold, Yinong Zong, Johannes Zeiser, Jie Zhou, Andreas Pich, Hans Bigalke, Thomas Binz, Andreas Rummel and Rongsheng Jin

Key motifs in Epstein-Barr virus (EBV)-encoded protein kinase for phosphorylation activity and nuclear localization

Svetlana Gershburg, Leann Murphy, Manfred Marschall and Edward Gershburg

Identification of the BCL2/Adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.

Gina B Scott, Paul A Bowles, Erica B Wilson, Josephine L Meade, Boon Chuan Low, Adam Davison, G. Eric Blair and Graham P Cook

Characterisation of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

Laura R Pearce, Gordon R Alton, Daniel T Richter, John C Kath, Laura Lingardo, Justin Chapman, Catherine Hwang and Dario R Alessi

A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA.

Sandro Altamura, Flavia D'Alessio, Barbara Selle and Martina Muckenthaler

11 August 2010

Contraction Regulates Site-Specific Phosphorylation of TBC1D1 in Skeletal Muscle

Kanokwan Vichaiwong, Suneet Purohit, Ding An, Taro Toyoda, Niels Jessen, Jianxin Xie, Michael F Hirshman and Laurie J Goodyear

Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis

Dana Morrone, Xiaoming Chen, Robert M Coates and Reuben J Peters

10 August 2010

Impairment of ATPase, adenine nucleotide translocator, and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy

Daniela Valenti, Apollonia Tullo, Mariano Francesco Caratozzolo, Riccardo Sandro Merafina, Paolo Scartezzini, Ersilia Marra and Rosa Anna Vacca

9 August 2010

Glucose promotion of GABA metabolism contributes to the stimulation of insulin secretion in b-cells

Javier Pizarro-Delgado, Matthias Braun, Ines Hernandez-Fisac, Rafael Martin-Del-Rio and Jorge Tamarit-Rodriguez

Munc18b regulates core SNARE complex assembly and constitutive exocytosis by interacting with the N-peptide and the closed-conformation C-terminus of syntaxin 3

Ren-Wang Peng, Claudio Guetg, Eric Abellan and Martin Fussenegger

The inhibition of Monocarboxylate Transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein

Matthew J Ovens, Christine Manoharan, Marieangela C Wilson, Clare M Murray and Andrew P Halestrap

6 August 2010

Epidermal growth factor down-regulates the expression of human hepatic stimulator substance via CCAAT/enhancer binding protein β in HepG2 cells

Ling-yue Dong, Guangyong Sun, Luan Jiang, Lei Shao, Yang Hu, Ying Jiang, Yutong Wang and Wei An

5 August 2010

Heart 6-phosphofructo-2-kinase activation by insulin requires protein kinase B but not serum- and glucocorticoid-inducible protein kinase-3

Véronique Mouton, Louise Toussaint, Didier Vertommen, Marie-Agnès Gueuning, Liliane Maisin, Xavier Havaux, Cossette Sanchez Canedo, Luc Bertrand, Franck Dequiedt, Brian A Hemmings, Louis Hue and Mark H Rider

Human INO80 chromatin remodeling complex contributes to DNA double strand break repair via the expression of Rad54B and XRCC3 genes

Eun-Jung Park, Shin-Kyoung Hur and Jongbum Kwon

3 August 2010

Accelerated Publication

Ring domain dimerization is essential for RNF4 function

Chu Wai Liew, Huaiyu Sun, Tony Hunter and Catherine L Day

2 August 2010

Molecular determination for selectivity of site-3 modulator (BmK I) to sodium channels from CNS: a clue to the importance of Na_v1.6 in BmK I-induced neuronal hyperexcitablity

Huiqiong He, ZhiRui Liu, Bangqian Dong, Jingjing Zhou, Hongyan Zhu and Yonghua Ji

30 July 2010

Porcine glutathione transferase Alpha 2-2 is a human GST A3-3 analogue that catalyses steroid double-bond isomerization

Natalia Fedulova, Françoise Raffalli-Mathieu and Bengt Mannervik

Characterization of the role of dendritic cells in prion transfer to primary neurons

Christelle Langevin, Karine Gousset, Maddalena Costanzo, Odile Richard Le Goff and Chiara Zurzolo

Cadmium regulates copper homeostasis by inhibiting the activity of Mac1, a transcriptional activator of the copper regulon, in Saccharomyces cerevisiae

Dong-Hyuk Heo, In-Joon Baek, Hyun-Jun Kang, Ji-Hyun Kim, Miwha Chang, Mi-Young Jeong, Tae-Hyoung Kim, Il-Dong Choi and Cheol-Won Yun

29 July 2010

Identification and biophysical assessment of the molecular recognition mechanisms between the human hemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X

Xiaoli Shi, Sandrine Opi, Adrien Lugari, Audrey Restouin, Thibault Coursindel, Isabelle Parrot, Javier Perez, Eric Madore, Pascale Zimmermann, Jacques Corbeil, Mingdong Huang, Stefan T Arold, Yves Collette and Xavier Morelli

Self-association and domain rearrangements between complement C3 and C3u provide insight into the activation mechanism of C3

Keying Li, Jayesh Gor and Stephen J Perkins

27 July 2010

The PedR transcriptional regulator interacts with thioredoxin to connect photosynthesis with gene expression in cyanobacteria

Mayumi Horiuchi, Kinu Nakamura, Kouji Kojima, Yoshitaka Nishiyama, Wakako Hatakeyama, Toru Hisabori and Yukako Hihara

Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 β-glucosidase from Kluyveromyces marxianus

Erina Yoshida, Masafumi Hidaka, Shinya Fushinobu, Takashi Koyanagi, Hiromichi Minami, Hisanori Tamaki, Motomitsu Kitaoka, Takane Katayama and Hidehiko Kumagai

26 July 2010

Characterization of an ATP regulated DNA-processing enzyme and thermotolerant phosphoesterase in the radioresistant bacterium Deinococcus radiodurans.

Swathi Kota, C Vijaya Kumar and Hari S Misra

Dissecting Ent3p: The ENTH domain binds different SNAREs via distinct amino acid residues while the C-terminus is sufficient for retrograde transport from endosomes

Jana Zimmermann, Subbulakshmi Chidambaram and Gabriele Fischer von Mollard

23 July 2010

Thrombin activated human platelets acutely generate oxidized docosahexaenoic acid-containing phospholipids via 12-lipoxygenase.

Lloyd Morgan, Christopher P Thomas, Hartmut Kuhn and V B O'Donnell

Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain

Jazmin Chiu-Ugalde, Franziska Theilig, Thomas Behrends, Julia Drebes, Carolin Sieland, Prema Subbarayal, Josef Köhrle, Annette Hammes, Lutz Schomburg and Ulrich Schweizer

Identification and characterization of PRG-1 as a neuronal calmodulin-binding protein

Hiroshi Tokumitsu, Naoya Hatano, Mitsumasa Tsuchiya, Saki Yurimoto, Tomohito Fujimoto, Naoki Ohara, Ryoji Kobayashi and Hiroyuki Sakagami

20 July 2010

Reactive site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: Biological and structural implications.

Ngee H. Lim, Masahide Kashiwagi, Robert Visse, Jonathan Jones, Jan J. Enghild, Keith Brew and Hideaki Nagase

Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors

Nyssa Drinkwater, Hoan Vu, Kimberly M Lovell, Kevin R Criscione, Brett Collins, Thomas Edward Prisinzano, Sally-Ann Poulsen, Michael J McLeish, Gary L Grunewald and Jennifer L Martin

15 July 2010

Sphingolipids mediate formation of mRNA processing bodies during the heat stress response of Saccharomyces cerevisiae

L. Ashley Cowart, Jason L. Gandy, Baby G Tholanikunnel and Yusuf A Hannun

Kinetic and thermodynamic resolution of the interactions between sulphite and the penta-heme cytochrome, NrfA, from Escherichia coli.

Gemma L Kemp, Thomas A Clarke, Sophie J Marritt, Colin Lockwood, Susannah R Poock, Andrew M Hemmings, David J Richardson, Myles Cheesman and Julea N Butt

29 September 2008

Curcumin, a dietary polyphenol, emerges as a novel inhibitor of DNA topoisomerase I of kinetoplastid parasite Leishmania donovani

Rakhee Das, Amit Roy, Agneyo Ganguly, Neeta Datta and Hemanta K Majumder