BJ Central Reviews with Animated Schemes

Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

Mario A. Shields, Surabhi Dangi‑Garimella, Amanda J. Redig and Hidayatullah G. Munshi..........541‑552

Published on the Internet 21 December 2011, doi:10.1042/BJ20111240

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Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

Brian Magnuson, Bilgen Ekim and Diane C. Fingar..........1‑21

Published on the Internet 14 December 2011, doi:10.1042/BJ20110892

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Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking

Paul Mellor, Levi A. Furber, Jennifer N. K. Nyarko and Deborah H. Anderson..........23‑37

Published on the Internet 14 December 2011, doi:10.1042/BJ20111164

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MeCP2 and Rett syndrome: reversibility and potential avenues for therapy

Kamal K.E. Gadalla, Mark E.S. Bailey and Stuart R. Cobb..........1‑14

Published on the Internet 14 September 2011, doi:10.1042/BJ20110648

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Aggregation of amyloids in a cellular context: modelling and experiment

Ran Friedman..........415‑426

Published as BJ Immediate Publication 26 August 2011, doi:10.1042/BJ20110369

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 Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities

Lyn‑Marie Birkholtz, Marni Williams, Jandeli Niemand, Abraham I. Louw, Lo Persson and Olle Heby..........229‑244

Published on the Internet 12 August 2011, doi:10.1042/BJ20110362

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Signal transduction by vascular endothelial growth factor receptors

Sina Koch, Sònia Tugues, Xiujuan Li, Laura Gualandi and Lena Claesson‑Welsh..........437, 169‑183

Published on the Internet 28 June 2011, doi:10.1042/BJ20110301

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Fibroblast growth factors and their receptors in cancer

Jørgen Wesche, Kaisa Haglund and Ellen Margrethe Haugsten..........437, 199‑213

Published on the Internet 28 June 2011, doi:10.1042/BJ20101603

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Super toxins from a super bug: structure and function of Clostridium difficile toxins

Abigail H. Davies, April K. Roberts, Clifford C. Shone and K. Ravi Acharya..........436, 517‑526

Published on the Internet 27 May 2011, doi:10.1042/BJ20110106

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Proteases as therapeutics

Charles S. Craik, Michael J. Page and Edwin L. Madison..........435, 1‑16

Published on the Internet 15 March 2011, doi:10.1042/BJ20100965

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Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

Min Ni, Yi Zhang and Amy S. Lee..........434, 181‑188

Published on the Internet 11 February 2011, doi:10.1042/BJ20101569

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The myotubularin family of lipid phosphatases in disease and in spermatogenesis

Dolores D. Mruk and C. Yan Cheng..........433, 253‑262

Published on the Internet 22 December 2010, doi:10.1042/BJ20101267

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TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs

Ian Robertson, Sacha Jensen and Penny Handford..........433, 263‑276

Published on the Internet 22 December 2010, doi:10.1042/BJ20101320

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The Golgi apparatus: an organelle with multiple complex functions

Cathal Wilson, Rossella Venditti, Laura R. Rega, Antonino Colanzi, Giovanni D'Angelo and M. Antonietta De Matteis..........433, 1‑9

Published on the Internet 15 December 2010, doi:10.1042/BJ20101058

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Rescuing neurons in prion disease

Nicholas C. Verity and Giovanna R. Mallucci..........433, 19‑29

Published on the Internet 15 December 2010, doi:10.1042/BJ20101323

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Unity and diversity in the human adenoviruses: exploiting alternative entry pathways for gene therapy

K. Hall, M. E. B. Zajdel and G. E. Blair..........431, 321‑336

Published on the Internet 11 October 2010, doi:10.1042/BJ20100766

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A nuclear glutathione cycle within the cell cycle

P. D. Vivancos, T. Wolff, J. Markovic, F. V. Pallardó and C. H. Foyer..........431, 169‑178

Published on the Internet 28 September 2010, doi:10.1042/BJ20100409

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Functional diversity of the hnRNPs: past, present and perspectives

S. Ping Han, Y. Hang Tang and R. Smith..........430, 379‑392

Published on the Internet 27 August 2010, doi:10.1042/BJ20100396

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Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore

A. Jaendling and R. J. McFarlane..........429, 225‑234

Published on the Internet 28 June 2010, doi:10.1042/BJ20100273

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Functional implications of sterol transport by the oxysterol-binding protein gene family

M. H. Ngo, T. R. Colbourne and N. D. Ridgway..........429, 13‑24

Published on the Internet 14 June 2010, doi:10.1042/BJ20100263

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Complexes between photoactivated rhodopsin and transducin: progress and questions

B. Jastrzebska, Y. Tsybovsky and K. Palczewski..........428, 1‑10

Published on the Internet 28 April 2010, doi:10.1042/BJ20100270

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Wnt signalling and the control of cellular metabolism

J. K. Sethi and A. Vidal‑Puig..........427,1‑17

Published on the Internet 15 March 2010, doi:10.1042/BJ20091866

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Rho GTPases: regulation of cell polarity and growth in yeasts

P. Perez and S. A. Rincón..........426,243‑253

Published on the Internet 24 February 2010, doi:10.1042/BJ20091823

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Poly(A)-binding protein (PABP): a common viral target

R. W. P. Smith and N. K. Gray..........426,1‑12

Published on the Internet 27 January 2010, doi:10.1042/BJ20091571

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Regulation of mRNA cap methylation

V. H. Cowling..........425,295‑302

Published on the Internet 23 December 2009, doi:10.1042/BJ20091352

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Transcriptional and post-translational regulation of adiponectin

M. Liu and F. Liu..........425,41‑52

Published on the Internet 14 December 2009, doi:10.1042/BJ20091045

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Regulation and function of selenoproteins in human disease

F. P. Bellinger, A. V. Raman, M. A. Reeves and M. J. Berry..........422,11‑22

Published on the Internet 29 July 2009, doi:10.1042/BJ20090219

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Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

S. Carpenter and L. A. J. O'Neill..........422,1‑10

Published on the Internet 29 July 2009, doi:10.1042/BJ20090616

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At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis

R. T. Youker, U. Shinde, R. Day and G. Thomas..........421, 1‑15

Published on the Internet 12 June 2009, doi:10.1042/BJ20081016

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Lateral organization of membrane proteins: tetraspanins spin their web

S. Charrin, F. le Naour, O. Silvie, P.‑E. Milhiet, C. Boucheix and E. Rubinstein..........420, 133‑154

Published on the Internet 13 May 2009, doi:10.1042/BJ20082422

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Connexin43 phosphorylation: structural changes and biological effects

J.L. Solan and P.D. Lampe..........419, 261–272

Published on the Internet 27 March 2009, doi:10.1042/BJ20082319

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The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

L.M. Ooms, K.A. Horan, P. Rahman, G. Seaton, R. Gurung, D.S. Kethesparan and C.A. Mitchell..........419, 29–49

Published on the Internet 13 March 2009, doi:10.1042/BJ20081673

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Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function

S.K. Dove, K. Dong, T. Kobayashi, F.K. Williams and R.H. Michell..........419, 1–13

Published on the Internet 13 March 2009, doi:10.1042/BJ20081950

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Dual-specificity phosphatases: critical regulators with diverse cellular targets

K.I. Patterson, T. Brummer, P.M. O'Brien and R.J. Daly..........418, 475–489

Published on the Internet 25 February 2009, doi:10.1042/BJ20082234

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Out, in and back again: PtdIns(4,5)P₂ regulates cadherin trafficking in epithelial morphogenesis

N.J. Schill and R.A. Anderson..........418, 247–260

Published on the Internet 11 February 2009, doi:10.1042/BJ20081844

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Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation

S.G. Ward and F.M. Marelli-Berg..........418, 13–27

Published on the Internet 28 January 2009, doi:10.1042/BJ20081969

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Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

M. Michalak, J. Groenendyk, E. Szabo, L.I. Gold and M. Opas..........417, 651–666

Published on the Internet 16 January 2009, doi:10.1042/BJ20081847

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The origin, evolution and structure of the protein world

G. Caetano-Anollés, M. Wang, D. Caetano-Anollés and J.E. Mittenthal..........417, 621–637

Published on the Internet 16 January 2009, doi:10.1042/BJ20082063

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Bicarbonate transport in cell physiology and disease

E. Cordat and J.R. Casey..........417, 423–439

Published on the Internet 23 December 2008, doi:10.1042/BJ20081634

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How mitochondria produce reactive oxygen species

M.P. Murphy..........417, 1–13

Published on the Internet 12 December 2008, doi:10.1042/BJ20081386

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Mechanisms of neuronal death in disease: defining the models and the players

E.M. Ribe, E. Serrano-Saiz, N. Akpan and C.M. Troy..........415, 165–182

Published on the Internet 25 September 2008, doi:10.1042/BJ20081118

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Glucose regulation of insulin gene expression in pancreatic β-cells

S.S. Andrali, M.L. Sampley, N.L. Vanderford and S. Özcan..........415, 1–10

Published on the Internet 12 September 2008, doi:10.1042/BJ20081029

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Regulation of gene expression in the nervous system

L. Ooi and I.C. Wood..........414, 327–341

Published on the Internet 27 August 2008, doi:10.1042/BJ20080963

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Regulation and function of triacylglycerol lipases in cellular metabolism

M.J. Watt and G.R. Steinberg..........414, 313–325

Published on the Internet 27 August 2008, doi:10.1042/BJ20080305

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Regulation of gene expression by hypoxia

N.S. Kenneth and S. Rocha..........414, 19–29

Published on the Internet 29 July 2008, doi:10.1042/BJ20081055

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Insulin action on glucose transporters through molecular switches, tracks and tethers

H. Zaid, C.N. Antonescu, V.K. Randhawa and A. Klip..........413, 201–215

Published on the Internet 26 June 2008; doi:10.1042/BJ20080723

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Neuropilins: structure, function and role in disease

C. Pellet-Many, P. Frankel, H. Jia and I. Zachary..........411, 211–226

Published on the Internet 27 March 2008, doi:10.1042/BJ20071639

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Liver fibrosis

K. Wallace, A.D. Burt and M.C. Wright..........411, 1–18

Published on the Internet 13 March 2008, doi:10.1042/BJ20071570

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Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment

M. O'Hayre, C.L. Salanga, T.M. Handel and S.J. Allen..........409, 635–649

Published on the Internet 15 January 2008, doi:10.1042/BJ20071493

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SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

E. Delpire and K.B.E. Gagnon..........409, 321–331

Published on the Internet 21 December 2007, doi:10.1042/BJ20071324

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Diacylglycerol kinases: at the hub of cell signalling

I. Mérida, A. Ávila-Flores and E. Merino..........409, 1–18

Published on the Internet 11 December 2007, doi:10.1042/BJ20071040

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Urinary-type plasminogen activator (uPA) and its receptor (uPAR) in squamous cell carcinoma of the oral cavity

Z. Shi and M.S. Stack..........407, 153–159

Published on the Internet 25 September 2007, doi:10.1042/BJ20071037

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Na⁺/Ca²⁺ exchangers: three mammalian gene families control Ca²⁺ transport

J. Lytton..........406, 365–382

Published on the Internet 29 August 2007, doi:10.1042/BJ20070619

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Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer

K.M. Wagstaff and D.A. Jans..........406, 185–202

Published on the Internet 13 August 2007, doi:10.1042/BJ20070505

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Controlling cell growth and survival through regulated nutrient transporter expression

A.L. Edinger..........406, 1–12

Published on the Internet 26 July 2007, doi:10.1042/BJ20070490

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Biosynthesis and metabolism of leukotrienes

R.C. Murphy and M.A. Gijón..........405, 379–395

Published on the Internet 13 July 2007, doi:10.1042/BJ20070289

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Structures and metal-ion-binding properties of the Ca²⁺-binding helix-loop-helix EF-hand motifs

J.L. Gifford, M.P. Walsh and H.J. Vogel..........405, 199–221

Published on the Internet 27 June 2007, doi:10.1042/BJ20070255

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Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1

G.L. Semenza..........405, 1–9

Published on the Internet 13 June 2007, doi:10.1042/BJ20070389

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The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation)

J.L. Brodsky..........404, 353–363

Published on the Internet 29 May 2007, doi:10.1042/BJ20061890

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Stem cells in the adult pancreas and liver

Z.D. Burke, S. Thowfeequ, M. Peran and D. Tosh..........404, 169–178

Published on the Internet 14 May 2007, doi:10.1042/BJ20070167

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Signalling to translation: how signal transduction pathways control the protein synthetic machinery

C.G. Proud..........403, 217–234

Published on the Internet 26 March 2007, doi:10.1042/BJ20070024

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Chimaerins: GAPs that bridge diacylglycerol signalling and the small G-protein Rac

C. Yang and M.G. Kazanietz..........403, 1–12

Published on the Internet 13 March 2007, doi:10.1042/BJ20061750

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Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P₂ pools

M. Santarius, C.H. Lee and R.A. Anderson..........398, 1–13

Published on the Internet 27 July 2006, doi:10.1042/BJ20060565

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Calcium-dependent and -independent interactions of the S100 protein family

L. Santamaria-Kisiel, A.C. Rintala-Dempsey and G.S. Shaw..........396, 201–214

Published on the Internet 15 May 2006, doi:10.1042/BJ20060195

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Life cycle of connexins in health and disease

D.W. Laird..........394, 527–543

Published on the Internet 24 February 2006, doi:10.1042/BJ20051922

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